MGP Database

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MGP001201

Ontology/Pathway Information

Entrez Gene ID2690
Gene Namegrowth hormone receptor
Gene Symbol GHR
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IDA:BHF-UCLCcell surface
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IDA:BHF-UCLCextracellular space
GO:0070195 IDA:BHF-UCLCgrowth hormone receptor complex
GO:0016021 IDA:BHF-UCLCintegral component of membrane
GO:0005887 IDA:BHF-UCLCintegral component of plasma membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0043235 IDA:BHF-UCLCreceptor complex
GO:0004896 IEA:InterProFcytokine receptor activity
GO:0019838 IPI:BHF-UCLFgrowth factor binding
GO:0017046 IPI:BHF-UCLFpeptide hormone binding
GO:0070064 ISS:BHF-UCLFproline-rich region binding
GO:0042803 IDA:BHF-UCLFprotein homodimerization activity
GO:0019901 ISS:BHF-UCLFprotein kinase binding
GO:0006103 ISS:BHF-UCLP2-oxoglutarate metabolic process
GO:0042977 ISS:BHF-UCLPactivation of JAK2 kinase activity
GO:0000187 ISS:BHF-UCLPactivation of MAPK activity
GO:0000255 ISS:BHF-UCLPallantoin metabolic process
GO:0032870 IMP:BHF-UCLPcellular response to hormone stimulus
GO:0006101 ISS:BHF-UCLPcitrate metabolic process
GO:0006600 ISS:BHF-UCLPcreatine metabolic process
GO:0046449 ISS:BHF-UCLPcreatinine metabolic process
GO:0006897 IEA:UniProtKB-KWPendocytosis
GO:0006631 ISS:BHF-UCLPfatty acid metabolic process
GO:0060396 IMP:BHF-UCLPgrowth hormone receptor signaling pathway
GO:0048009 IMP:BHF-UCLPinsulin-like growth factor receptor signaling pathway
GO:0006549 ISS:BHF-UCLPisoleucine metabolic process
GO:0007259 ISS:BHF-UCLPJAK-STAT cascade
GO:0060397 TAS:ReactomePJAK-STAT cascade involved in growth hormone signaling pathway
GO:0044236 IMP:BHF-UCLPmulticellular organismal metabolic process
GO:0006107 ISS:BHF-UCLPoxaloacetate metabolic process
GO:0040018 IMP:BHF-UCLPpositive regulation of multicellular organism growth
GO:0050731 ISS:BHF-UCLPpositive regulation of peptidyl-tyrosine phosphorylation
GO:0042517 ISS:BHF-UCLPpositive regulation of tyrosine phosphorylation of Stat3 protein
GO:0042523 ISS:BHF-UCLPpositive regulation of tyrosine phosphorylation of Stat5 protein
GO:0031623 IDA:BHF-UCLPreceptor internalization
GO:0040014 ISS:BHF-UCLPregulation of multicellular organism growth
GO:0046898 IDA:BHF-UCLPresponse to cycloheximide
GO:0032355 IDA:BHF-UCLPresponse to estradiol
GO:0006105 ISS:BHF-UCLPsuccinate metabolic process
GO:0019530 ISS:BHF-UCLPtaurine metabolic process
GO:0006573 ISS:BHF-UCLPvaline metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75790Cytokine Signaling in Immune system
REACT_111133Growth hormone receptor signaling
REACT_6900Immune System
REACT_116022Nuclear signaling by ERBB4
REACT_115697Prolactin receptor signaling
REACT_115596Signaling by ERBB4
REACT_111102Signal Transduction
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