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MGP001229

Record overview

MGPD IDMGP001229
Gene ID2739
SpeciesHomo sapiens (Human)
Gene Nameglyoxalase I
Gene Symbol GLO1
SynonymsGLYI; GLOD1; HEL-S-74;
Alternate nameslactoylglutathione lyase; S-D-lactoylglutathione methylglyoxal lyase; aldoketomutase; epididymis secretory protein Li 74; glx I; glyoxalase domain containing 1; ketone-aldehyde mutase; lactoyl glutathione lyase; methylglyoxalase;
Chromosome6
Map Location6p21.3-p21.1
EC Number4.4.1.5
SummaryThe enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for GLO1

Proteins

lactoylglutathione lyase
Refseq ID:NP_006699
Protein GI:118402586
UniProt ID:Q04760
mRNA ID:NM_006708
Length:184
RefSeq Status:
MAEPQPPSGGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLE
LTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM
 
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