MGP Database

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MGP001236

Ontology/Pathway Information

Entrez Gene ID2746
Gene Nameglutamate dehydrogenase 1
Gene Symbol GLUD1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:BHF-UCLCcytoplasm
GO:0005759 TAS:ReactomeCmitochondrial matrix
GO:0005739 IDA:UniProtKBCmitochondrion
GO:0043531 IDA:BHF-UCLFADP binding
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0004352 IDA:UniProtKBFglutamate dehydrogenase (NAD+) activity
GO:0004353 IDA:BHF-UCLFglutamate dehydrogenase [NAD(P)+] activity
GO:0005525 IDA:BHF-UCLFGTP binding
GO:0042802 TAS:BHF-UCLFidentical protein binding
GO:0070728 IDA:BHF-UCLFleucine binding
GO:0070403 IDA:BHF-UCLFNAD+ binding
GO:0008652 TAS:ReactomePcellular amino acid biosynthetic process
GO:0034641 TAS:ReactomePcellular nitrogen compound metabolic process
GO:0006537 IDA:BHF-UCLPglutamate biosynthetic process
GO:0006538 IDA:UniProtKBPglutamate catabolic process
GO:0006541 ISS:UniProtKBPglutamine metabolic process
GO:0032024 IMP:BHF-UCLPpositive regulation of insulin secretion
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0021762 IEP:UniProtKBPsubstantia nigra development
GO:0072350 ISS:UniProtKBPtricarboxylic acid metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_238Amino acid synthesis and interconversion (transamination)
REACT_111217Metabolism
REACT_13Metabolism of amino acids and derivatives
SMP Pathway Links
SMP IDDescription
SMP001362-Hydroxyglutric Aciduria (D And L Form)
SMP002434-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency
SMP00009Ammonia Recycling
SMP00020Arginine and Proline Metabolism
SMP00362Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency)
SMP00357Argininemia
SMP00003Argininosuccinic Aciduria
SMP00002Carbamoyl Phosphate Synthetase Deficiency
SMP00001Citrullinemia Type I
SMP00504Creatine deficiency, guanidinoacetate methyltransferase deficiency
SMP00127Glucose-Alanine Cycle
SMP00072Glutamate Metabolism
SMP00188Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency)
SMP00385Homocarnosinosis
SMP00339Hyperinsulinism-Hyperammonemia Syndrome
SMP00506Hyperornithinemia-hyperammonemia-homocitrullinuria [HHH-syndrome]
SMP00505Hyperornithinemia with gyrate atrophy (HOGA)
SMP00361Hyperprolinemia Type I
SMP00360Hyperprolinemia Type II
SMP00507L-arginine:glycine amidinotransferase deficiency
SMP00363Ornithine Aminotransferase Deficiency (OAT Deficiency)
SMP00205Ornithine Transcarbamylase Deficiency (OTC Deficiency)
SMP00207Prolidase Deficiency (PD)
SMP00208Prolinemia Type II
SMP00567Succinic semialdehyde dehydrogenase deficiency
SMP00059Urea Cycle
SMP00654Warburg Effect
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