MGP Database

MGP001243

Ontology/Pathway Information

Entrez Gene ID2769
Gene Nameguanine nucleotide binding protein (G protein), alpha 15 (Gq class)
Gene Symbol GNA15
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005834 NAS:UniProtKBCheterotrimeric G-protein complex
GO:0005886 TAS:ReactomeCplasma membrane
GO:0031683 IBA:GO_CentralFG-protein beta/gamma-subunit complex binding
GO:0001664 IBA:GO_CentralFG-protein coupled receptor binding
GO:0003924 IBA:GO_CentralFGTPase activity
GO:0005525 IEA:UniProtKB-KWFGTP binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0004871 IGI:UniProtKBFsignal transducer activity
GO:0007202 TAS:ProtIncPactivation of phospholipase C activity
GO:0007188 IBA:GO_CentralPadenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007596 TAS:ReactomePblood coagulation
GO:0060158 IBA:GO_CentralPphospholipase C-activating dopamine receptor signaling pathway
GO:0007207 TAS:ProtIncPphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
GO:0030168 TAS:ReactomePplatelet activation
GO:0007204 IGI:UniProtKBPpositive regulation of cytosolic calcium ion concentration
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18405Acetylcholine regulates insulin secretion
REACT_19140ADP signalling through P2Y purinoceptor 1
REACT_19193Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
REACT_19375Free fatty acids regulate insulin secretion
REACT_18283G alpha (q) signalling events
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_19184GPCR downstream signaling
REACT_604Hemostasis
REACT_1505Integration of energy metabolism
REACT_111217Metabolism
REACT_798Platelet activation, signaling and aggregation
REACT_18325Regulation of insulin secretion
REACT_20524Signal amplification
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
REACT_21384Thrombin signalling through proteinase activated receptors (PARs)
REACT_20647Thromboxane signalling through TP receptor
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