MGP Database

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MGP001250

Ontology/Pathway Information

Entrez Gene ID2778
Gene NameGNAS complex locus
Gene Symbol GNAS
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005576 IEA:UniProtKB-SubCellCextracellular region
GO:0005634 IDA:UniProtKBCnucleus
GO:0048471 IDA:UniProtKBCperinuclear region of cytoplasm
GO:0030133 IEA:UniProtKB-SubCellCtransport vesicle
GO:0007565 NAS:UniProtKBPfemale pregnancy
GO:0040015 ISS:UniProtKBPnegative regulation of multicellular organism growth
GO:0009306 NAS:UniProtKBPprotein secretion
GO:0071107 IMP:UniProtKBPresponse to parathyroid hormone
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_23887Aquaporin-mediated transport
REACT_18372Class B/2 (Secretin family receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_19231G alpha (i) signalling events
REACT_19327G alpha (s) signalling events
REACT_19333G alpha (z) signalling events
REACT_18274Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
REACT_1665Glucagon signaling in metabolic regulation
REACT_18377Glucagon-type ligand receptors
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_268323Hedgehog 'off' state
REACT_604Hemostasis
REACT_1505Integration of energy metabolism
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_111217Metabolism
REACT_1946PKA activation in glucagon signalling
REACT_23876Platelet homeostasis
REACT_23946Prostacyclin signalling through prostacyclin receptor
REACT_18325Regulation of insulin secretion
REACT_14797Signaling by GPCR
REACT_264508Signaling by Hedgehog
REACT_111102Signal Transduction
REACT_15518Transmembrane transport of small molecules
REACT_24023Vasopressin regulates renal water homeostasis via Aquaporins
SMP Pathway Links
SMP IDDescription
SMP00310Corticotropin Activation of Cortisol Production
SMP00308Dopamine Activation of Neurological Reward System
SMP00309Excitatory Neural Signalling Through 5-HTR 4 and Serotonin
SMP00312Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
SMP00311Excitatory Neural Signalling Through 5-HTR 7 and Serotonin
SMP00320Intracellular Signalling Through Adenosine Receptor A2a and Adenosine
SMP00321Intracellular Signalling Through Adenosine Receptor A2b and Adenosine
SMP00333Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone
SMP00335Intracellular Signalling Through Histamine H2 Receptor and Histamine
SMP00338Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin
SMP00343Intracellular Signalling Through PGD2 receptor and Prostaglandin D2
SMP00354Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin
SMP00322Vasopressin Regulation of Water Homeostasis
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