MGP Database

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MGP001262

UniProt Annotations

Entry Information
Gene Nameguanine nucleotide binding protein (G protein), gamma 11
Protein EntryGBG11_HUMAN
UniProt IDP61952
SpeciesHuman
Comments
Comment typeDescription
FunctionGuanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
SimilarityBelongs to the G protein gamma family. {ECO:0000305}.
Subcellular LocationCell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
SubunitG proteins are composed of 3 units, alpha, beta and gamma. Interacts with beta-1 and beta-3, but not with beta-2.
Tissue SpecificityAbundantly expressed in all tissues tested except for brain.
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