MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP001279

UniProt Annotations

Entry Information
Gene Nameglycerol-3-phosphate dehydrogenase 2 (mitochondrial)
Protein EntryGPDM_HUMAN
UniProt IDP43304
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=P43304-1; Sequence=Displayed; Name=2; IsoId=P43304-2; Sequence=VSP_017134;
Catalytic Activitysn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.
CofactorName=FAD; Xref=ChEBI:CHEBI:57692;
Enzyme RegulationCalcium-binding enhance the activity of the enzyme.
PathwayPolyol metabolism; glycerol degradation via glycerol kinase pathway; glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1.
Sequence CautionSequence=BAD92636.1; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityBelongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. {ECO:0000305}.
SimilarityContains 2 EF-hand domains. {ECO:0000255|PROSITE- ProRule:PRU00448}.
Subcellular LocationMitochondrion.
  logo