MGP Database

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MGP001300

Ontology/Pathway Information

Entrez Gene ID2869
Gene NameG protein-coupled receptor kinase 5
Gene Symbol GRK5
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005925 IDA:HPACfocal adhesion
GO:0031965 IDA:HPACnuclear membrane
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 IDA:HPACnucleus
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0004703 IEA:UniProtKB-ECFG-protein coupled receptor kinase activity
GO:0005543 TAS:ProtIncFphospholipid binding
GO:0005080 TAS:ProtIncFprotein kinase C binding
GO:0004674 IDA:UniProtKBFprotein serine/threonine kinase activity
GO:0007188 TAS:ProtIncPadenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0006915 IEA:UniProtKB-KWPapoptotic process
GO:0043066 IDA:UniProtKBPnegative regulation of apoptotic process
GO:0046777 IDA:UniProtKBPprotein autophosphorylation
GO:0008277 TAS:ProtIncPregulation of G-protein coupled receptor protein signaling pathway
GO:0007217 IDA:BHF-UCLPtachykinin receptor signaling pathway
GO:0038032 IEA:InterProPtermination of G-protein coupled receptor signaling pathway
GO:0016055 IEA:UniProtKB-KWPWnt signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18283G alpha (q) signalling events
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_19184GPCR downstream signaling
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
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