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MGP001305

UniProt Annotations

Entry Information
Gene Nameglutathione peroxidase 3 (plasma)
Protein EntryGPX3_HUMAN
UniProt IDP22352
SpeciesHuman
Comments
Comment typeDescription
Catalytic Activity2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O.
FunctionProtects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.
PtmThe N-terminus is blocked.
SimilarityBelongs to the glutathione peroxidase family. {ECO:0000305}.
Subcellular LocationSecreted.
SubunitHomotetramer.
Tissue SpecificitySecreted in plasma.
Web ResourceName=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/gpx3/";
Web ResourceName=Wikipedia; Note=Glutathione peroxidase entry; URL="http://en.wikipedia.org/wiki/Glutathione_peroxidase";
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