MGP Database

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MGP001310

Ontology/Pathway Information

Entrez Gene ID2887
Gene Namegrowth factor receptor-bound protein 10
Gene Symbol GRB10
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 TAS:ProtIncCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005886 TAS:ProtIncCplasma membrane
GO:0005158 ISS:BHF-UCLFinsulin receptor binding
GO:0005070 TAS:ProtIncFSH3/SH2 adaptor activity
GO:0048009 IEA:EnsemblPinsulin-like growth factor receptor signaling pathway
GO:0008286 ISS:BHF-UCLPinsulin receptor signaling pathway
GO:0046325 ISS:BHF-UCLPnegative regulation of glucose import
GO:0045719 ISS:BHF-UCLPnegative regulation of glycogen biosynthetic process
GO:0046627 ISS:BHF-UCLPnegative regulation of insulin receptor signaling pathway
GO:0042326 IEA:EnsemblPnegative regulation of phosphorylation
GO:0030178 IDA:UniProtKBPnegative regulation of Wnt signaling pathway
GO:0042327 ISS:BHF-UCLPpositive regulation of phosphorylation
GO:0030949 IDA:UniProtKBPpositive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0032868 ISS:BHF-UCLPresponse to insulin
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_1195Insulin receptor signalling cascade
REACT_570IRS activation
REACT_762IRS-related events
REACT_1661SHC activation
REACT_999SHC-related events
REACT_508Signal attenuation
REACT_498Signaling by Insulin receptor
REACT_111040Signaling by SCF-KIT
REACT_111102Signal Transduction
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