MGP Database

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MGP001326

Ontology/Pathway Information

Entrez Gene ID2908
Gene Namenuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
Gene Symbol NR3C1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 IEA:EnsemblCcytosol
GO:0016020 IEA:EnsemblCmembrane
GO:0005759 TAS:ProtIncCmitochondrial matrix
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0038051 IDA:UniProtKBFglucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity
GO:0004883 TAS:ProtIncFglucocorticoid receptor activity
GO:0000978 IDA:NTNU_SBFRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA:UniProtKBFRNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003700 IDA:UniProtKBFsequence-specific DNA binding transcription factor activity
GO:0005496 IDA:UniProtKBFsteroid binding
GO:1990239 IDA:UniProtKBFsteroid hormone binding
GO:0008270 IEA:InterProFzinc ion binding
GO:0030325 IEA:EnsemblPadrenal gland development
GO:0071383 IDA:UniProtKBPcellular response to steroid hormone stimulus
GO:0016568 IEA:UniProtKB-KWPchromatin modification
GO:0010467 TAS:ReactomePgene expression
GO:0008211 IEA:EnsemblPglucocorticoid metabolic process
GO:0060603 IEA:EnsemblPmammary gland duct morphogenesis
GO:1900170 IEA:EnsemblPnegative regulation of glucocorticoid mediated signaling pathway
GO:0043525 IEA:EnsemblPpositive regulation of neuron apoptotic process
GO:0045944 IDA:UniProtKBPpositive regulation of transcription from RNA polymerase II promoter
GO:0031946 IEA:EnsemblPregulation of glucocorticoid biosynthetic process
GO:0006111 IEA:EnsemblPregulation of gluconeogenesis
GO:0006355 IDA:UniProtKBPregulation of transcription, DNA-templated
GO:0007165 TAS:ProtIncPsignal transduction
GO:0006351 TAS:ProtIncPtranscription, DNA-templated
GO:0006366 TAS:ProtIncPtranscription from RNA polymerase II promoter
GO:0006367 TAS:ReactomePtranscription initiation from RNA polymerase II promoter
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111118BMAL1:CLOCK,NPAS2 activates circadian gene expression
REACT_24941Circadian Clock
SMP Pathway Links
SMP IDDescription
SMP00441Prednisolone Action Pathway
SMP00632Prednisolone Metabolism Pathway
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