MGP Database

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MGP001383

Ontology/Pathway Information

Entrez Gene ID2990
Gene Nameglucuronidase, beta
Gene Symbol GUSB
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0043231 IDA:HPACintracellular membrane-bounded organelle
GO:0043202 TAS:ReactomeClysosomal lumen
GO:0016020 IDA:UniProtKBCmembrane
GO:0004566 TAS:ReactomeFbeta-glucuronidase activity
GO:0019904 IPI:AgBaseFprotein domain specific binding
GO:0005102 IPI:AgBaseFreceptor binding
GO:0005975 TAS:ReactomePcarbohydrate metabolic process
GO:0006027 TAS:ReactomePglycosaminoglycan catabolic process
GO:0030203 TAS:ReactomePglycosaminoglycan metabolic process
GO:0030214 TAS:ReactomePhyaluronan catabolic process
GO:0030212 TAS:ReactomePhyaluronan metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_268678Defective B3GAT3 causes JDSSDHD
REACT_268431Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
REACT_268749Defective B4GALT7 causes EDS, progeroid type
REACT_267917Defective CHST14 causes EDS, musculocontractural type
REACT_267648Defective CHST3 causes SEDCJD
REACT_268786Defective CHST6 causes MCDC1
REACT_268113Defective CHSY1 causes TPBS
REACT_267942Defective EXT1 causes exostoses 1, TRPS2 and CHDS
REACT_267741Defective EXT2 causes exostoses 2
REACT_268843Defective PAPSS2 causes SEMD-PA
REACT_268059Defective SLC26A2 causes chondrodysplasias
REACT_116125Disease
REACT_268624Diseases associated with glycosaminoglycan metabolism
REACT_268324Diseases of glycosylation
REACT_264090Glycogen storage diseases
REACT_121315Glycosaminoglycan metabolism
REACT_121314Heparan sulfate/heparin (HS-GAG) metabolism
REACT_120752HS-GAG degradation
REACT_121083Hyaluronan metabolism
REACT_120996Hyaluronan uptake and degradation
REACT_111217Metabolism
REACT_474Metabolism of carbohydrates
REACT_147857MPS I - Hurler syndrome
REACT_147734MPS II - Hunter syndrome
REACT_147753MPS IIIA - Sanfilippo syndrome A
REACT_147788MPS IIIB - Sanfilippo syndrome B
REACT_147860MPS IIIC - Sanfilippo syndrome C
REACT_147749MPS IIID - Sanfilippo syndrome D
REACT_147825MPS IV - Morquio syndrome A
REACT_147798MPS IV - Morquio syndrome B
REACT_147739MPS IX - Natowicz syndrome
REACT_147759MPS VII - Sly syndrome
REACT_147719MPS VI - Maroteaux-Lamy syndrome
REACT_147853Mucopolysaccharidoses
REACT_264430Myoclonic epilepsy of Lafora
SMP Pathway Links
SMP IDDescription
SMP00344Acute Intermittent Porphyria
SMP00345Congenital Erythropoietic Porphyria (CEP) or Gunther Disease
SMP00553Glycogenosis, Type III. Cori disease, Debrancher glycogenosis
SMP00554Glycogenosis, Type IV. Amylopectinosis, Anderson disease
SMP00555Glycogenosis, Type VI. Hers disease
SMP00552Glycogen synthetase deficiency
SMP00342Hereditary Coproporphyria (HCP)
SMP00556Mucopolysaccharidosis VI. Sly syndrome
SMP00346Porphyria Variegata (PV)
SMP00024Porphyrin Metabolism
SMP00058Starch and Sucrose Metabolism
SMP00557Sucrase-isomaltase deficiency
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