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MGP001403

Record overview

MGPD IDMGP001403
Gene ID3021
SpeciesHomo sapiens (Human)
Gene NameH3 histone, family 3B (H3.3B)
Gene Symbol H3F3B
SynonymsH3.3B;
Alternate nameshistone H3.3;
Chromosome17
Map Location17q25.1
SummaryHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded by this gene is a member of the histone H3 family. Pseudogenes of this gene have been identified on the X chromosome, and on chromosomes 5, 13 and 17. [provided by RefSeq, Jan 2015]
OrthologsView orthologs and multiple alignments for H3F3B

Proteins

histone H3.3
Refseq ID:NP_005315
Protein GI:4885385
UniProt ID:P84243
mRNA ID:NM_005324
Length:136
RefSeq Status:
MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAY
LVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
 
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