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MGP001417

Record overview

MGPD IDMGP001417
Gene ID3045
SpeciesHomo sapiens (Human)
Gene Namehemoglobin, delta
Gene Symbol HBD
Alternate nameshemoglobin subunit delta; delta globin; delta-globin chain; hemoglobin delta chain;
Chromosome11
Map Location11p15.5
SummaryThe delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon--Ggamma--Agamma--delta--beta-3'. Mutations in the delta-globin gene are associated with beta-thalassemia. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for HBD

Proteins

hemoglobin subunit delta
Refseq ID:NP_000510
Protein GI:4504351
UniProt ID:P02042
mRNA ID:NM_000519
Length:147
RefSeq Status:
MVHLTPEEKTAVNALWGKVNVDAVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMGNPKVKAHGKKVLGAFSDGLAHLDNLKGTFSQLSELHCDKLHVD
PENFRLLGNVLVCVLARNFGKEFTPQMQAAYQKVVAGVANALAHKYH
 
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