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MGP001480

Record overview

MGPD IDMGP001480
Gene ID3177
SpeciesHomo sapiens (Human)
Gene Namesolute carrier family 29 (equilibrative nucleoside transporter), member 2
Gene Symbol SLC29A2
SynonymsENT2; DER12; HNP36;
Alternate namesequilibrative nucleoside transporter 2; 36 kDa nucleolar protein HNP36; delayed-early response protein 12; equilibrative NBMPR-insensitive nucleoside transporter; equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter; hydrophobic nucleolar protein, 36 kDa; hydrophobic nucleolar protein, 36kD; nucleoside transporter, ei-type; solute carrier family 29 (nucleoside transporters), member 2; solute carrier family 29 member 2;
Chromosome11
Map Location11q13
SummaryThe uptake of nucleosides by transporters, such as SLC29A2, is essential for nucleotide synthesis by salvage pathways in cells that lack de novo biosynthetic pathways. Nucleoside transport also plays a key role in the regulation of many physiologic processes through its effect on adenosine concentration at the cell surface (Griffiths et al., 1997 [PubMed 9396714]).[supplied by OMIM, Nov 2008]
OrthologsView orthologs and multiple alignments for SLC29A2

Proteins

equilibrative nucleoside transporter 2 isoform a
Refseq ID:NP_001523
Protein GI:38708299
UniProt ID:Q14542
mRNA ID:NM_001532
Length:456
RefSeq Status:
MARGDAPRDSYHLVGISFFILGLGTLLPWNFFITAIPYFQARLAGAGNSTARILSTNHTGPEDAFNFNNWVTLLSQLPLLLFTLLNSFLYQCVPETVRIL
GSLLAILLLFALTAALVKVDMSPGPFFSITMASVCFINSFSAVLQGSLFGQLGTMPSTYSTLFLSGQGLAGIFAALAMLLSMASGVDAETSALGYFITPC
VGILMSIVCYLSLPHLKFARYYLANKSSQAQAQELETKAELLQSDENGIPSSPQKVALTLDLDLEKEPESEPDEPQKPGKPSVFTVFQKIWLTALCLVLV
FTVTLSVFPAITAMVTSSTSPGKWSQFFNPICCFLLFNIMDWLGRSLTSYFLWPDEDSRLLPLLVCLRFLFVPLFMLCHVPQRSRLPILFPQDAYFITFM
LLFAVSNGYLVSLTMCLAPRQVLPHEREVAGALMTFFLALGLSCGASLSFLFKALL
 
equilibrative nucleoside transporter 2 isoform a
Refseq ID:NP_001287797
Protein GI:665505946
UniProt ID:Q14542
mRNA ID:NM_001300868
Length:456
RefSeq Status:
Protein sequence is identical to GI:38708299 (mRNA isoform)
 
equilibrative nucleoside transporter 2 isoform b
Refseq ID:NP_001287798
Protein GI:664805964
UniProt ID:Q96FB2
mRNA ID:NM_001300869
Length:361
RefSeq Status:
MARGDAPRDSYHLVGISFFILGLGTLLPWNFFITAIPYFQARLAGAGNSTARILSTNHTGPEDAFNFNNWVTLLSQLPLLLFTLLNSFLYQCVPETVRIL
GSLLAILLLFALTAALVKVDMSPGPFFSITMASVCFINSFSAVLQGSLFGQLGTMPSTYSTLFLSGQGLAGIFAALAMLLSMASGVDAETSALGYFITPC
VGILMSIVCYLSLPHLKFARYYLANKSSQAQAQELETKAELLQSDLADSAVPCVGLHSHPVRLPRHHSHGDQLHQSWEVESVLQPHLLLPPLQHHGLAGT
EPDLLLPVARRGQPAAAPAGLPAVPVRAPLHAVPRAPEVPAAHPLPTGCLLHHLHAALCRF
 
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