MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP001506

Ontology/Pathway Information

Entrez Gene ID3290
Gene Namehydroxysteroid (11-beta) dehydrogenase 1
Gene Symbol HSD11B1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0016020 IDA:UniProtKBCmembrane
GO:0070524 IEA:UniProtKB-ECF11-beta-hydroxysteroid dehydrogenase (NADP+) activity
GO:0003845 TAS:ReactomeF11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity
GO:0006704 TAS:ReactomePglucocorticoid biosynthetic process
GO:0030324 IEA:EnsemblPlung development
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0008202 TAS:ReactomePsteroid metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_11036Glucocorticoid biosynthesis
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_11057Metabolism of steroid hormones and vitamin D
SMP Pathway Links
SMP IDDescription
SMP0057511-beta-hydroxylase deficiency (CYP11B1)
SMP0056617-alpha-hydroxylase deficiency (CYP17)
SMP0057621-hydroxylase deficiency (CYP21)
SMP007183-Beta-Hydroxysteroid Dehydrogenase Deficiency
SMP00373Adrenal Hyperplasia Type 3 or Congenital Adrenal Hyperplasia due to 21-hydroxylase Deficiency
SMP00372Adrenal Hyperplasia Type 5 or Congenital Adrenal Hyperplasia due to 17 Alpha-hydroxylase Deficiency
SMP00717Apparent mineralocorticoid excess syndrome
SMP00371Congenital Lipoid Adrenal Hyperplasia (CLAH) or Lipoid CAH
SMP00577Corticosterone methyl oxidase I deficiency (CMO I)
SMP00578Corticosterone methyl oxidase II deficiency - CMO II
SMP00130Steroidogenesis
  logo