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MGP Database

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MGP001507

Ontology/Pathway Information

Entrez Gene ID	3291
Gene Name	hydroxysteroid (11-beta) dehydrogenase 2
Gene Symbol	HSD11B2
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005783	IEA:UniProtKB-SubCell	C	endoplasmic reticulum
GO:0003845	IEA:Ensembl	F	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity
GO:0051287	IEA:Ensembl	F	NAD binding
GO:0005496	IEA:Ensembl	F	steroid binding
GO:0007565	IEA:Ensembl	P	female pregnancy
GO:0006704	TAS:ProtInc	P	glucocorticoid biosynthetic process
GO:0002017	IEA:Ensembl	P	regulation of blood volume by renal aldosterone
GO:0042493	IEA:Ensembl	P	response to drug
GO:0032094	IEA:Ensembl	P	response to food
GO:0051384	IEA:Ensembl	P	response to glucocorticoid
GO:0001666	IEA:Ensembl	P	response to hypoxia
GO:0032868	IEA:Ensembl	P	response to insulin

SMP Pathway Links

SMP ID	Description
SMP00575	11-beta-hydroxylase deficiency (CYP11B1)
SMP00566	17-alpha-hydroxylase deficiency (CYP17)
SMP00576	21-hydroxylase deficiency (CYP21)
SMP00718	3-Beta-Hydroxysteroid Dehydrogenase Deficiency
SMP00373	Adrenal Hyperplasia Type 3 or Congenital Adrenal Hyperplasia due to 21-hydroxylase Deficiency
SMP00372	Adrenal Hyperplasia Type 5 or Congenital Adrenal Hyperplasia due to 17 Alpha-hydroxylase Deficiency
SMP00717	Apparent mineralocorticoid excess syndrome
SMP00371	Congenital Lipoid Adrenal Hyperplasia (CLAH) or Lipoid CAH
SMP00577	Corticosterone methyl oxidase I deficiency (CMO I)
SMP00578	Corticosterone methyl oxidase II deficiency - CMO II
SMP00130	Steroidogenesis