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MGP001509

Record overview

MGPD IDMGP001509
Gene ID3293
SpeciesHomo sapiens (Human)
Gene Namehydroxysteroid (17-beta) dehydrogenase 3
Gene Symbol HSD17B3
SynonymsEDH17B3; SDR12C2;
Alternate namestestosterone 17-beta-dehydrogenase 3; 17-beta-HSD 3; 17-beta-HSD3; 17-beta-hydroxysteroid dehydrogenase type 3; short chain dehydrogenase/reductase family 12C, member 2; testicular 17-beta-hydroxysteroid dehydrogenase;
Chromosome9
Map Location9q22
EC Number1.1.1.64
SummaryThis isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for HSD17B3

Proteins

testosterone 17-beta-dehydrogenase 3
Refseq ID:NP_000188
Protein GI:4557649
UniProt ID:P37058
mRNA ID:NM_000197
Length:310
RefSeq Status:
MGDVLEQFFILTGLLVCLACLAKCVRFSRCVLLNYWKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSV
KIIQADFTKDDIYEHIKEKLAGLEIGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSA
SKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTKYLNTNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAFQRLLLTHYV
AYLKLNTKVR
 
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