MGP Database

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MGP001517

Ontology/Pathway Information

Entrez Gene ID3312
Gene Nameheat shock 70kDa protein 8
Gene Symbol HSPA8
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0072562 IDA:UniProtKBCblood microparticle
GO:0061202 TAS:ReactomeCclathrin-sculpted gamma-aminobutyric acid transport vesicle membrane
GO:0005829 IDA:UniProtKBCcytosol
GO:0005615 IDA:UniProtKBCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0005622 NAS:UniProtKBCintracellular
GO:0042470 IEA:UniProtKB-SubCellCmelanosome
GO:0016020 IDA:UniProtKBCmembrane
GO:0005730 IEA:UniProtKB-SubCellCnucleolus
GO:0005634 IDA:UniProtKBCnucleus
GO:0005886 TAS:ReactomeCplasma membrane
GO:0000974 IDA:UniProtKBCPrp19 complex
GO:0030529 IDA:UniProtKBCribonucleoprotein complex
GO:0005681 IEA:UniProtKB-KWCspliceosomal complex
GO:0016887 IDA:BHF-UCLFATPase activity
GO:0042623 NAS:UniProtKBFATPase activity, coupled
GO:0005524 IDA:BHF-UCLFATP binding
GO:0019899 IPI:BHF-UCLFenzyme binding
GO:0001664 IPI:ParkinsonsUK-UCLFG-protein coupled receptor binding
GO:0031072 IPI:BHF-UCLFheat shock protein binding
GO:0023026 IDA:UniProtKBFMHC class II protein complex binding
GO:0044822 IDA:UniProtKBFpoly(A) RNA binding
GO:0031625 IPI:ParkinsonsUK-UCLFubiquitin protein ligase binding
GO:0051082 IDA:UniProtKBFunfolded protein binding
GO:0006200 IDA:BHF-UCLPATP catabolic process
GO:0007411 TAS:ReactomePaxon guidance
GO:0051085 IEA:EnsemblPchaperone mediated protein folding requiring cofactor
GO:0072318 IEA:EnsemblPclathrin coat disassembly
GO:0010467 TAS:ReactomePgene expression
GO:0061024 TAS:ReactomePmembrane organization
GO:0016071 TAS:ReactomePmRNA metabolic process
GO:0006397 IEA:UniProtKB-KWPmRNA processing
GO:1902904 IDA:BHF-UCLPnegative regulation of fibril organization
GO:0045892 IDA:UniProtKBPnegative regulation of transcription, DNA-templated
GO:0007269 TAS:ReactomePneurotransmitter secretion
GO:0006892 TAS:ReactomePpost-Golgi vesicle-mediated transport
GO:0006457 NAS:UniProtKBPprotein folding
GO:0042026 IDA:UniProtKBPprotein refolding
GO:0051726 IEA:EnsemblPregulation of cell cycle
GO:0006986 NAS:UniProtKBPresponse to unfolded protein
GO:0016070 TAS:ReactomePRNA metabolic process
GO:0008380 IEA:UniProtKB-KWPRNA splicing
GO:0007268 TAS:ReactomePsynaptic transmission
GO:0006351 IEA:UniProtKB-KWPtranscription, DNA-templated
GO:0016032 IEA:UniProtKB-KWPviral process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_264075Attenuation phase
REACT_25325AUF1 (hnRNP D0) destabilizes mRNA
REACT_18266Axon guidance
REACT_120956Cellular responses to stress
REACT_263897Cellular response to heat stress
REACT_22292CHL1 interactions
REACT_19187Clathrin derived vesicle budding
REACT_111045Developmental Biology
REACT_23947GABA synthesis, release, reuptake and degradation
REACT_71Gene Expression
REACT_19400Golgi Associated Vesicle Biogenesis
REACT_264164HSF1-dependent transactivation
REACT_22205L1CAM interactions
REACT_19287Lysosome Vesicle Biogenesis
REACT_11123Membrane Trafficking
REACT_1735mRNA Splicing
REACT_467mRNA Splicing - Major Pathway
REACT_13685Neuronal System
REACT_13723Neurotransmitter Release Cycle
REACT_125Processing of Capped Intron-Containing Pre-mRNA
REACT_264487Regulation of HSF1-mediated heat shock response
REACT_24994Regulation of mRNA stability by proteins that bind AU-rich elements
REACT_11235trans-Golgi Network Vesicle Budding
REACT_13477Transmission across Chemical Synapses
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