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MGP001543

UniProt Annotations

Entry Information
Gene Nameisoleucyl-tRNA synthetase
Protein EntrySYIC_HUMAN
UniProt IDP41252
SpeciesHuman
Comments
Comment typeDescription
Catalytic ActivityATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile).
InteractionP07814:EPRS; NbExp=5; IntAct=EBI-355303, EBI-355315;
Sequence CautionSequence=BAA05835.1; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityBelongs to the class-I aminoacyl-tRNA synthetase family. {ECO:0000305}.
Subcellular LocationCytoplasm {ECO:0000269|PubMed:7721108}.
SubunitPart of a multisubunit complex that groups tRNA ligases for Arg, Asp, Glu, Gln, Ile, Leu, Lys, Met and Pro.
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