MGP Database

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MGP001556

UniProt Annotations

Entry Information
Gene Nameisocitrate dehydrogenase 3 (NAD+) gamma
Protein Entry
UniProt IDP51553
SpeciesHuman
Comments
Comment typeDescription
Catalytic ActivityIsocitrate + NAD(+) = 2-oxoglutarate + CO(2) + NADH. {ECO:0000256|RuleBase:RU361266}.
CofactorName=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|RuleBase:RU361266}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000256|RuleBase:RU361266}; Note=Binds 1 Mg(2+) or Mn(2+) ion per subunit. {ECO:0000256|RuleBase:RU361266};
SimilarityBelongs to the isocitrate and isopropylmalate dehydrogenases family. {ECO:0000256|RuleBase:RU004443}.
Subcellular LocationMitochondrion {ECO:0000256|RuleBase:RU361266}.
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