MGP Database

MGP001605

Ontology/Pathway Information

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0009897	IEA:Ensembl	C	external side of plasma membrane
GO:0016021	IEA:UniProtKB-KW	C	integral component of membrane
GO:0005886	TAS:Reactome	C	plasma membrane
GO:0008144	IEA:Ensembl	F	drug binding
GO:0019976	IBA:GO_Central	F	interleukin-2 binding
GO:0004911	TAS:ProtInc	F	interleukin-2 receptor activity
GO:0006924	IEA:Ensembl	P	activation-induced cell death of T cells
GO:0006915	TAS:ProtInc	P	apoptotic process
GO:0008283	TAS:ProtInc	P	cell proliferation
GO:0007166	TAS:ProtInc	P	cell surface receptor signaling pathway
GO:0006955	TAS:ProtInc	P	immune response
GO:0006954	IBA:GO_Central	P	inflammatory response
GO:0002437	IEA:Ensembl	P	inflammatory response to antigenic stimulus
GO:0038110	TAS:GOC	P	interleukin-2-mediated signaling pathway
GO:0050687	IEA:Ensembl	P	negative regulation of defense response to virus
GO:0050777	IEA:Ensembl	P	negative regulation of immune response
GO:0050728	IEA:Ensembl	P	negative regulation of inflammatory response
GO:0042130	IEA:Ensembl	P	negative regulation of T cell proliferation
GO:0007219	IEA:Ensembl	P	Notch signaling pathway
GO:0042104	IEA:Ensembl	P	positive regulation of activated T cell proliferation
GO:0045582	IEA:Ensembl	P	positive regulation of T cell differentiation
GO:0046013	IEA:Ensembl	P	regulation of T cell homeostatic proliferation

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_75790	Cytokine Signaling in Immune system
REACT_19290	G beta:gamma signalling through PI3Kgamma
REACT_19184	GPCR downstream signaling
REACT_19388	G-protein beta:gamma signalling
REACT_1695	GPVI-mediated activation cascade
REACT_604	Hemostasis
REACT_6900	Immune System
REACT_27283	Interleukin-2 signaling
REACT_23837	Interleukin-3, 5 and GM-CSF signaling
REACT_23891	Interleukin receptor SHC signaling
REACT_798	Platelet activation, signaling and aggregation
REACT_14797	Signaling by GPCR
REACT_22232	Signaling by Interleukins
REACT_111102	Signal Transduction