MGP Database

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MGP001633

UniProt Annotations

Entry Information
Gene Nameinositol polyphosphate-1-phosphatase
Protein EntryINPP_HUMAN
UniProt IDP49441
SpeciesHuman
Comments
Comment typeDescription
Catalytic Activity1D-myo-inositol 1,4-bisphosphate + H(2)O = 1D- myo-inositol 4-phosphate + phosphate.
CofactorName=Mg(2+); Xref=ChEBI:CHEBI:18420;
Enzyme RegulationInhibited by Li(+).
PathwaySignal transduction; phosphatidylinositol signaling pathway.
SimilarityBelongs to the inositol monophosphatase family. {ECO:0000305}.
SubunitMonomer. {ECO:0000250}.
Tissue SpecificityUbiquitously expressed, with highest levels in pancreas and kidney.
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