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MGP001636

Record overview

MGPD IDMGP001636
Gene ID3632
SpeciesHomo sapiens (Human)
Gene Nameinositol polyphosphate-5-phosphatase, 40kDa
Gene Symbol INPP5A
Synonyms5PTASE;
Alternate namestype I inositol 1,4,5-trisphosphate 5-phosphatase; 43 kDa inositol polyphosphate 5-phophatase; CTCL tumor antigen HD-CL-02; InsP3 5-phosphatase; inositol polyphosphate-5-phosphatase, 40kD; inositol trisphosphate-5-phosphatase, 40kD; type I inositol-1,4,5-trisphosphate 5-phophatase; type I inositol-1,4,5-trisphosphate 5-phosphatase;
Chromosome10
Map Location10q26.3
EC Number3.1.3.56
SummaryThe protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for INPP5A

Proteins

type I inositol 1,4,5-trisphosphate 5-phosphatase
Refseq ID:NP_005530
Protein GI:109702906
UniProt ID:Q14642
mRNA ID:NM_005539
Length:412
RefSeq Status:
MAGKAAAPGTAVLLVTANVGSLFDDPENLQKNWLREFYQVVHTHKPHFMALHCQEFGGKNYEASMSHVDKFVKELLSSDAMKEYNRARVYLDENYKSQEH
FTALGSFYFLHESLKNIYQFDFKAKKYRKVAGKEIYSDTLESTPMLEKEKFPQDYFPECKWSRKGFIRTRWCIADCAFDLVNIHLFHDASNLVAWETSPS
VYSGIRHKALGYVLDRIIDQRFEKVSYFVFGDFNFRLDSKSVVETLCTKATMQTVRAADTNEVVKLIFRESDNDRKVMLQLEKKLFDYFNQEVFRDNNGT
ALLEFDKELSVFKDRLYELDISFPPSYPYSEDARQGEQYMNTRCPAWCDRILMSPSAKELVLRSESEEKVVTYDHIGPNVCMGDHKPVFLAFRIMPGAGK
PHAHVHKCCVVQ
 
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