MGP Database

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MGP001642

Ontology/Pathway Information

Entrez Gene ID3642
Gene Nameinsulinoma-associated 1
Gene Symbol INSM1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 ISS:UniProtKBCnucleus
GO:0017053 IDA:UniProtKBCtranscriptional repressor complex
GO:0031490 IDA:UniProtKBFchromatin DNA binding
GO:0001047 IDA:UniProtKBFcore promoter binding
GO:0030332 IPI:UniProtKBFcyclin binding
GO:0042826 IPI:UniProtKBFhistone deacetylase binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0000978 IDA:NTNU_SBFRNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IDA:NTNU_SBFRNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003700 IDA:UniProtKBFsequence-specific DNA binding transcription factor activity
GO:0061104 ISS:UniProtKBPadrenal chromaffin cell differentiation
GO:0007049 IEA:UniProtKB-KWPcell cycle
GO:0031018 TAS:ReactomePendocrine pancreas development
GO:0008285 IDA:UniProtKBPnegative regulation of cell proliferation
GO:0001933 IDA:UniProtKBPnegative regulation of protein phosphorylation
GO:0000122 IDA:UniProtKBPnegative regulation of transcription from RNA polymerase II promoter
GO:0003358 ISS:UniProtKBPnoradrenergic neuron development
GO:0042421 ISS:UniProtKBPnorepinephrine biosynthetic process
GO:0003310 ISS:UniProtKBPpancreatic A cell differentiation
GO:0071158 IDA:UniProtKBPpositive regulation of cell cycle arrest
GO:0045597 ISS:UniProtKBPpositive regulation of cell differentiation
GO:2000179 ISS:UniProtKBPpositive regulation of neural precursor cell proliferation
GO:0010468 ISS:UniProtKBPregulation of gene expression
GO:0043254 IDA:UniProtKBPregulation of protein complex assembly
GO:0061549 ISS:UniProtKBPsympathetic ganglion development
GO:0060290 IDA:UniProtKBPtransdifferentiation
GO:0003323 IEA:EnsemblPtype B pancreatic cell development
GO:0003309 ISS:UniProtKBPtype B pancreatic cell differentiation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111045Developmental Biology
REACT_13698Regulation of beta-cell development
REACT_13650Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells
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