MGP Database

MGP001647

Ontology/Pathway Information

Entrez Gene ID	3655
Gene Name	integrin, alpha 6
Gene Symbol	ITGA6
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0009925	IEA:Ensembl	C	basal plasma membrane
GO:0005604	IEA:Ensembl	C	basement membrane
GO:0005913	IEA:Ensembl	C	cell-cell adherens junction
GO:0009986	IDA:UniProtKB	C	cell surface
GO:0009897	IEA:Ensembl	C	external side of plasma membrane
GO:0030175	IEA:Ensembl	C	filopodium
GO:0005925	IDA:UniProtKB	C	focal adhesion
GO:0030056	IEA:Ensembl	C	hemidesmosome
GO:0034676	IEA:Ensembl	C	integrin alpha6-beta4 complex
GO:0005886	IDA:BHF-UCL	C	plasma membrane
GO:0046872	IEA:UniProtKB-KW	F	metal ion binding
GO:0097186	IMP:UniProtKB	P	amelogenesis
GO:0007596	TAS:Reactome	P	blood coagulation
GO:0050873	IEA:Ensembl	P	brown fat cell differentiation
GO:0033627	IEA:Ensembl	P	cell adhesion mediated by integrin
GO:0034329	TAS:Reactome	P	cell junction assembly
GO:0007160	IEA:Ensembl	P	cell-matrix adhesion
GO:0031589	IMP:UniProtKB	P	cell-substrate adhesion
GO:0007044	TAS:ProtInc	P	cell-substrate junction assembly
GO:0031668	IEA:Ensembl	P	cellular response to extracellular stimulus
GO:0071407	IEA:Ensembl	P	cellular response to organic cyclic compound
GO:0048565	IMP:UniProtKB	P	digestive tract development
GO:0010668	IEP:UniProtKB	P	ectodermal cell differentiation
GO:0030198	TAS:Reactome	P	extracellular matrix organization
GO:0046847	IEA:Ensembl	P	filopodium assembly
GO:0031581	TAS:Reactome	P	hemidesmosome assembly
GO:0007229	IEA:UniProtKB-KW	P	integrin-mediated signaling pathway
GO:0050900	TAS:Reactome	P	leukocyte migration
GO:0035878	IMP:UniProtKB	P	nail development
GO:2001237	IMP:BHF-UCL	P	negative regulation of extrinsic apoptotic signaling pathway
GO:0043065	IGI:MGI	P	positive regulation of apoptotic process
GO:0022409	IEA:Ensembl	P	positive regulation of cell-cell adhesion
GO:0010811	IEA:Ensembl	P	positive regulation of cell-substrate adhesion
GO:0042327	IMP:BHF-UCL	P	positive regulation of phosphorylation
GO:0045944	IMP:BHF-UCL	P	positive regulation of transcription from RNA polymerase II promoter
GO:0072001	IMP:UniProtKB	P	renal system development
GO:0016337	IEA:Ensembl	P	single organismal cell-cell adhesion
GO:0043588	IMP:UniProtKB	P	skin development

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_150180	Assembly of collagen fibrils and other multimeric structures
REACT_12560	Basigin interactions
REACT_111155	Cell-Cell communication
REACT_20676	Cell junction organization
REACT_12051	Cell surface interactions at the vascular wall
REACT_120729	Collagen formation
REACT_118779	Extracellular matrix organization
REACT_604	Hemostasis
REACT_13552	Integrin cell surface interactions
REACT_169262	Laminin interactions
REACT_163874	Non-integrin membrane-ECM interactions
REACT_163942	Syndecan interactions
REACT_20537	Type I hemidesmosome assembly