MGP Database

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MGP001654

Ontology/Pathway Information

Entrez Gene ID3664
Gene Nameinterferon regulatory factor 6
Gene Symbol IRF6
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005634 IEA:UniProtKB-SubCellCnucleus
GO:0003677 ISS:UniProtKBFDNA binding
GO:0000975 IEA:InterProFregulatory region DNA binding
GO:0003700 ISS:UniProtKBFsequence-specific DNA binding transcription factor activity
GO:0007050 IDA:UniProtKBPcell cycle arrest
GO:0048468 IEA:EnsemblPcell development
GO:0019221 TAS:ReactomePcytokine-mediated signaling pathway
GO:0060333 TAS:ReactomePinterferon-gamma-mediated signaling pathway
GO:0030216 IEA:EnsemblPkeratinocyte differentiation
GO:0043616 IEA:EnsemblPkeratinocyte proliferation
GO:0060644 ISS:UniProtKBPmammary gland epithelial cell differentiation
GO:0008285 IDA:UniProtKBPnegative regulation of cell proliferation
GO:0045893 ISS:UniProtKBPpositive regulation of transcription, DNA-templated
GO:0006351 IEA:UniProtKB-KWPtranscription, DNA-templated
GO:0060337 TAS:ReactomePtype I interferon signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75790Cytokine Signaling in Immune system
REACT_6900Immune System
REACT_25162Interferon alpha/beta signaling
REACT_25078Interferon gamma signaling
REACT_25229Interferon Signaling
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