MGP Database

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MGP001682

Ontology/Pathway Information

Entrez Gene ID3704
Gene Nameinosine triphosphatase (nucleoside triphosphate pyrophosphatase)
Gene Symbol ITPA
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0035870 EXP:ReactomeFdITP diphosphatase activity
GO:0036220 EXP:ReactomeFITP diphosphatase activity
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0000166 IEA:UniProtKB-KWFnucleotide binding
GO:0036222 EXP:ReactomeFXTP diphosphatase activity
GO:0051276 IEA:EnsemblPchromosome organization
GO:0009204 IEA:UniProtKB-HAMAPPdeoxyribonucleoside triphosphate catabolic process
GO:0006193 IEA:EnsemblPITP catabolic process
GO:0055086 TAS:ReactomePnucleobase-containing small molecule metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111217Metabolism
REACT_1698Metabolism of nucleotides
SMP Pathway Links
SMP IDDescription
SMP00535Adenine phosphoribosyltransferase deficiency (APRT)
SMP00144Adenosine Deaminase Deficiency
SMP00167Adenylosuccinate Lyase Deficiency
SMP00168AICA-Ribosiduria
SMP00427Azathioprine Action Pathway
SMP00172Beta Ureidopropionase Deficiency
SMP00178Dihydropyrimidinase Deficiency
SMP00365Gout or Kelley-Seegmiller Syndrome
SMP00364Lesch-Nyhan Syndrome (LNS)
SMP00428Mercaptopurine Action Pathway
SMP00536Mitochondrial DNA depletion syndrome
SMP00202MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)
SMP00203Molybdenum Cofactor Deficiency
SMP00537Myoadenylate deaminase deficiency
SMP00050Purine Metabolism
SMP00210Purine Nucleoside Phosphorylase Deficiency
SMP00046Pyrimidine Metabolism
SMP00430Thioguanine Action Pathway
SMP00219UMP Synthase Deiciency (Orotic Aciduria)
SMP00220Xanthine Dehydrogenase Deficiency (Xanthinuria)
SMP00512Xanthinuria type I
SMP00513Xanthinuria type II
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