MGP Database

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MGP001703

Ontology/Pathway Information

Entrez Gene ID3741
Gene Namepotassium channel, voltage gated shaker related subfamily A, member 5
Gene Symbol KCNA5
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005783 IEA:EnsemblCendoplasmic reticulum
GO:0005794 IDA:UniProtKBCGolgi apparatus
GO:0014704 IDA:BHF-UCLCintercalated disc
GO:0046691 IEA:EnsemblCintracellular canaliculus
GO:0045121 IDA:BHF-UCLCmembrane raft
GO:0048471 IEA:EnsemblCperinuclear region of cytoplasm
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0008076 IDA:BHF-UCLCvoltage-gated potassium channel complex
GO:0030018 IEA:EnsemblCZ disc
GO:0051393 IPI:BHF-UCLFalpha-actinin binding
GO:0005251 IDA:BHF-UCLFdelayed rectifier potassium channel activity
GO:0015271 IDA:BHF-UCLFoutward rectifier potassium channel activity
GO:0019870 IEA:EnsemblFpotassium channel inhibitor activity
GO:0019901 IPI:BHF-UCLFprotein kinase binding
GO:0097110 IPI:BHF-UCLFscaffold protein binding
GO:0086089 IMP:BHF-UCLFvoltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
GO:0086014 IMP:BHF-UCLPatrial cardiac muscle cell action potential
GO:0060081 IMP:BHF-UCLPmembrane hyperpolarization
GO:0051481 IEA:EnsemblPnegative regulation of cytosolic calcium ion concentration
GO:0043267 IEA:EnsemblPnegative regulation of potassium ion transport
GO:1900087 IEA:EnsemblPpositive regulation of G1/S transition of mitotic cell cycle
GO:2000288 IEA:EnsemblPpositive regulation of myoblast proliferation
GO:0071435 IDA:BHF-UCLPpotassium ion export
GO:0055075 IEA:EnsemblPpotassium ion homeostasis
GO:0006813 IDA:MGIPpotassium ion transport
GO:0051260 IEA:InterProPprotein homooligomerization
GO:0060372 IMP:BHF-UCLPregulation of atrial cardiac muscle cell membrane repolarization
GO:0086091 IMP:BHF-UCLPregulation of heart rate by cardiac conduction
GO:0050796 TAS:BHF-UCLPregulation of insulin secretion
GO:0042391 IDA:BHF-UCLPregulation of membrane potential
GO:0043266 IMP:BHF-UCLPregulation of potassium ion transport
GO:0019229 IEA:EnsemblPregulation of vasoconstriction
GO:0001666 IEA:EnsemblPresponse to hypoxia
GO:0007268 TAS:ReactomePsynaptic transmission
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_13685Neuronal System
REACT_75908Potassium Channels
REACT_75770Voltage gated Potassium channels
SMP Pathway Links
SMP IDDescription
SMP00296Acebutolol Action Pathway
SMP00297Alprenolol Action Pathway
SMP00665Amiodarone Action Pathway
SMP00376Amlodipine Action Pathway
SMP00664Arbutamine Action Pathway
SMP00298Atenolol Action Pathway
SMP00299Betaxolol Action Pathway
SMP00668Bevantolol Action Pathway
SMP00300Bisoprolol Action Pathway
SMP00657Bopindolol Action Pathway
SMP00670Bupranolol Action Pathway
SMP00658Carteolol Action Pathway
SMP00367Carvedilol Action Pathway
SMP00359Diltiazem Action Pathway
SMP00325Disopyramide Action Pathway
SMP00662Dobutamine Action Pathway
SMP00661Epinephrine Action Pathway
SMP00301Esmolol Action Pathway
SMP00377Felodipine Action Pathway
SMP00331Flecainide Action Pathway
SMP00326Fosphenytoin (Antiarrhythmic) Action Pathway
SMP00332Ibutilide Action Pathway
SMP00663Isoprenaline Action Pathway
SMP00378Isradipine Action Pathway
SMP00368Labetalol Action Pathway
SMP00666Levobunolol Action Pathway
SMP00328Lidocaine (Antiarrhythmic) Action Pathway
SMP00667Metipranolol Action Pathway
SMP00302Metoprolol Action Pathway
SMP00329Mexiletine Action Pathway
SMP00588Muscle/Heart Contraction
SMP00303Nadolol Action Pathway
SMP00366Nebivolol Action Pathway
SMP00379Nifedipine Action Pathway
SMP00380Nimodipine Action Pathway
SMP00381Nisoldipine Action Pathway
SMP00382Nitrendipine Action Pathway
SMP00304Oxprenolol Action Pathway
SMP00305Penbutolol Action Pathway
SMP00327Phenytoin (Antiarrhythmic) Action Pathway
SMP00306Pindolol Action Pathway
SMP00669Practolol Action Pathway
SMP00324Procainamide (Antiarrhythmic) Action Pathway
SMP00307Propranolol Action Pathway
SMP00323Quinidine Action Pathway
SMP00660Sotalol Action Pathway
SMP00659Timolol Action Pathway
SMP00330Tocainide Action Pathway
SMP00375Verapamil Action Pathway
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