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MGP001723

Record overview

MGPD IDMGP001723
Gene ID3762
SpeciesHomo sapiens (Human)
Gene Namepotassium channel, inwardly rectifying subfamily J, member 5
Gene Symbol KCNJ5
SynonymsCIR; GIRK4; KATP1; LQT13; KIR3.4;
Alternate namesG protein-activated inward rectifier potassium channel 4; IRK-4; cardiac ATP-sensitive potassium channel; heart KATP channel; inward rectifier K+ channel KIR3.4; potassium inwardly-rectifying channel, subfamily J, member 5;
Chromosome11
Map Location11q24
SummaryPotassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It may associate with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for KCNJ5

Proteins

G protein-activated inward rectifier potassium channel 4
Refseq ID:NP_000881
Protein GI:24797141
UniProt ID:P48544
mRNA ID:NM_000890
Length:419
RefSeq Status:
MAGDSRNAMNQDMEIGVTPWDPKKIPKQARDYVPIATDRTRLLAEGKKPRQRYMEKSGKCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVT
WLFFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETL
MFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSPFWEMSQAQLHQEEFE
VVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQ
NEEDEPKGLGGSREARGSV
 
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