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MGP001725

Record overview

MGPD IDMGP001725
Gene ID3764
SpeciesHomo sapiens (Human)
Gene Namepotassium channel, inwardly rectifying subfamily J, member 8
Gene Symbol KCNJ8
SynonymsKIR6.1; uKATP-1;
Alternate namesATP-sensitive inward rectifier potassium channel 8; inward rectifier K(+) channel Kir6.1; inwardly rectifying potassium channel KIR6.1; potassium channel, inwardly rectifying subfamily J member 8; potassium inwardly-rectifying channel, subfamily J, member 8;
Chromosome12
Map Location12p11.23
SummaryPotassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. Defects in this gene may be a cause of J-wave syndromes and sudden infant death syndrome (SIDS). [provided by RefSeq, May 2012]
OrthologsView orthologs and multiple alignments for KCNJ8

Proteins

ATP-sensitive inward rectifier potassium channel 8
Refseq ID:NP_004973
Protein GI:4826802
UniProt ID:Q15842
mRNA ID:NM_004982
Length:424
RefSeq Status:
MLARKSIIPEEYVLARIAAENLRKPRIRDRLPKARFIAKSGACNLAHKNIREQGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLVAFAHGD
IYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIA
VRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVV
ETTGITTQARTSYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARELDEKPSILIQTLQKSELSHQNSLRKRNSMRRNNSMRRNNSIRR
NNSSLMVPKVQFMTPEGNQNTSES
 
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