MGP Database

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MGP001728

Ontology/Pathway Information

Entrez Gene ID3767
Gene Namepotassium channel, inwardly rectifying subfamily J, member 11
Gene Symbol KCNJ11
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0008282 IDA:BHF-UCLCATP-sensitive potassium channel complex
GO:0030673 IEA:EnsemblCaxolemma
GO:0070852 IEA:EnsemblCcell body fiber
GO:0005829 IEA:EnsemblCcytosol
GO:0005783 IEA:EnsemblCendoplasmic reticulum
GO:0005768 IEA:EnsemblCendosome
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0014704 IEA:EnsemblCintercalated disc
GO:0005739 IEA:EnsemblCmitochondrion
GO:0043209 IEA:EnsemblCmyelin sheath
GO:0043025 IEA:EnsemblCneuronal cell body
GO:0005635 IEA:EnsemblCnuclear envelope
GO:0005886 IDA:BHF-UCLCplasma membrane
GO:0030315 ISS:BHF-UCLCT-tubule
GO:0008076 IDA:BHF-UCLCvoltage-gated potassium channel complex
GO:0030506 IPI:BHF-UCLFankyrin binding
GO:0015272 ISS:BHF-UCLFATP-activated inward rectifier potassium channel activity
GO:0005524 ISS:BHF-UCLFATP binding
GO:0044325 IPI:BHF-UCLFion channel binding
GO:0030955 TAS:BHF-UCLFpotassium ion binding
GO:0005249 IDA:BHF-UCLFvoltage-gated potassium channel activity
GO:0071333 IEA:EnsemblPcellular response to glucose stimulus
GO:0071316 IEA:EnsemblPcellular response to nicotine
GO:0071356 IEA:EnsemblPcellular response to tumor necrosis factor
GO:0006112 TAS:ReactomePenergy reserve metabolic process
GO:0006006 IMP:BHF-UCLPglucose metabolic process
GO:0046676 IMP:BHF-UCLPnegative regulation of insulin secretion
GO:0050877 IMP:BHF-UCLPneurological system process
GO:2001259 IEA:EnsemblPpositive regulation of cation channel activity
GO:0010107 ISS:BHF-UCLPpotassium ion import
GO:0071805 IDA:BHF-UCLPpotassium ion transmembrane transport
GO:0050796 IMP:BHF-UCLPregulation of insulin secretion
GO:0034765 IBA:GO_CentralPregulation of ion transmembrane transport
GO:0042391 IDA:BHF-UCLPregulation of membrane potential
GO:0033198 IDA:BHF-UCLPresponse to ATP
GO:0042493 IMP:BHF-UCLPresponse to drug
GO:0032355 IEA:EnsemblPresponse to estradiol
GO:0002931 IEA:EnsemblPresponse to ischemia
GO:0033574 IEA:EnsemblPresponse to testosterone
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0007268 TAS:ReactomePsynaptic transmission
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75775ATP sensitive Potassium channels
REACT_1505Integration of energy metabolism
REACT_75918Inwardly rectifying K+ channels
REACT_111217Metabolism
REACT_13685Neuronal System
REACT_75908Potassium Channels
REACT_18325Regulation of insulin secretion
SMP Pathway Links
SMP IDDescription
SMP00296Acebutolol Action Pathway
SMP00297Alprenolol Action Pathway
SMP00665Amiodarone Action Pathway
SMP00376Amlodipine Action Pathway
SMP00664Arbutamine Action Pathway
SMP00298Atenolol Action Pathway
SMP00299Betaxolol Action Pathway
SMP00668Bevantolol Action Pathway
SMP00300Bisoprolol Action Pathway
SMP00657Bopindolol Action Pathway
SMP00670Bupranolol Action Pathway
SMP00658Carteolol Action Pathway
SMP00367Carvedilol Action Pathway
SMP00359Diltiazem Action Pathway
SMP00325Disopyramide Action Pathway
SMP00662Dobutamine Action Pathway
SMP00661Epinephrine Action Pathway
SMP00301Esmolol Action Pathway
SMP00377Felodipine Action Pathway
SMP00331Flecainide Action Pathway
SMP00326Fosphenytoin (Antiarrhythmic) Action Pathway
SMP00332Ibutilide Action Pathway
SMP00663Isoprenaline Action Pathway
SMP00378Isradipine Action Pathway
SMP00368Labetalol Action Pathway
SMP00666Levobunolol Action Pathway
SMP00328Lidocaine (Antiarrhythmic) Action Pathway
SMP00667Metipranolol Action Pathway
SMP00302Metoprolol Action Pathway
SMP00329Mexiletine Action Pathway
SMP00588Muscle/Heart Contraction
SMP00303Nadolol Action Pathway
SMP00366Nebivolol Action Pathway
SMP00379Nifedipine Action Pathway
SMP00380Nimodipine Action Pathway
SMP00381Nisoldipine Action Pathway
SMP00382Nitrendipine Action Pathway
SMP00304Oxprenolol Action Pathway
SMP00305Penbutolol Action Pathway
SMP00327Phenytoin (Antiarrhythmic) Action Pathway
SMP00306Pindolol Action Pathway
SMP00669Practolol Action Pathway
SMP00324Procainamide (Antiarrhythmic) Action Pathway
SMP00307Propranolol Action Pathway
SMP00323Quinidine Action Pathway
SMP00660Sotalol Action Pathway
SMP00659Timolol Action Pathway
SMP00330Tocainide Action Pathway
SMP00375Verapamil Action Pathway
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