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MGP001731

UniProt Annotations

Entry Information
Gene Namepotassium channel, inwardly rectifying subfamily J, member 15
Protein EntryKCJ15_HUMAN
UniProt IDQ99712
SpeciesHuman
Comments
Comment typeDescription
FunctionInward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
InteractionQ63ZW7:Inadl (xeno); NbExp=4; IntAct=EBI-7082607, EBI-8366894;
SimilarityBelongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ15 subfamily. {ECO:0000305}.
Subcellular LocationMembrane; Multi-pass membrane protein.
SubunitInteracts with INADL. {ECO:0000269|PubMed:9647694}.
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