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MGP001749

Record overview

MGPD IDMGP001749
Gene ID3795
SpeciesHomo sapiens (Human)
Gene Nameketohexokinase (fructokinase)
Gene Symbol KHK
Alternate namesketohexokinase; hepatic fructokinase;
Chromosome2
Map Location2p23.3
EC Number2.7.1.3
SummaryThis gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for KHK

Proteins

ketohexokinase isoform a
Refseq ID:NP_000212
Protein GI:4557693
UniProt ID:P50053
mRNA ID:NM_000221
Length:298
RefSeq Status:
MEEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFVLDDLRRYSVDLRYTVFQTTGSVPIATVI
INEASGSRTILYYDRSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLG
FQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV
 
ketohexokinase isoform b
Refseq ID:NP_006479
Protein GI:5670342
UniProt ID:P50053
mRNA ID:NM_006488
Length:298
RefSeq Status:
MEEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGHVADFLVADFRRRGVDVSQVAWQSKGDTPSSCCI
INNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDVAKHLG
FQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTFNASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIV
 
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