MGP Database

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MGP001768

Ontology/Pathway Information

Entrez Gene ID3818
Gene Namekallikrein B, plasma (Fletcher factor) 1
Gene Symbol KLKB1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005576 NAS:UniProtKBCextracellular region
GO:0005615 IDA:BHF-UCLCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005886 TAS:ReactomeCplasma membrane
GO:0004252 TAS:ProtIncFserine-type endopeptidase activity
GO:0007596 TAS:ReactomePblood coagulation
GO:0007597 TAS:ReactomePblood coagulation, intrinsic pathway
GO:0022617 TAS:ReactomePextracellular matrix disassembly
GO:0030198 TAS:ReactomePextracellular matrix organization
GO:0002542 TAS:BHF-UCLPFactor XII activation
GO:0042730 IEA:UniProtKB-KWPfibrinolysis
GO:0031639 IDA:BHF-UCLPplasminogen activation
GO:0051919 IDA:BHF-UCLPpositive regulation of fibrinolysis
GO:0006508 TAS:ProtIncPproteolysis
GO:0031638 TAS:BHF-UCLPzymogen activation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_118682Activation of Matrix Metalloproteinases
REACT_118572Degradation of the extracellular matrix
REACT_118779Extracellular matrix organization
REACT_2051Formation of Fibrin Clot (Clotting Cascade)
REACT_604Hemostasis
REACT_326Intrinsic Pathway
SMP Pathway Links
SMP IDDescription
SMP00269Acenocoumarol Action Pathway
SMP00280Alteplase Action Pathway
SMP00286Aminocaproic Acid Action Pathway
SMP00281Anistreplase Action Pathway
SMP00288Aprotinin Action Pathway
SMP00275Ardeparin Action Pathway
SMP00276Argatroban Action Pathway
SMP00277Bivalirudin Action Pathway
SMP00586Coagulation
SMP00656Dicoumarol Action Pathway
SMP00270Dicumarol Action Pathway
SMP00272Enoxaparin Action Pathway
SMP00273Fondaparinux Action Pathway
SMP00274Heparin Action Pathway
SMP00278Lepirudin Action Pathway
SMP00655Phenindione Action Pathway
SMP00271Phenprocoumon Action Pathway
SMP00285Reteplase Action Pathway
SMP00282Streptokinase Action Pathway
SMP00283Tenecteplase Action Pathway
SMP00287Tranexamic Acid Action Pathway
SMP00284Urokinase Action Pathway
SMP00268Warfarin Action Pathway
SMP00279Ximelagatran Action Pathway
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