MGP Database

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MGP001815

Ontology/Pathway Information

Entrez Gene ID3973
Gene Nameluteinizing hormone/choriogonadotropin receptor
Gene Symbol LHCGR
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005768 TAS:ProtIncCendosome
GO:0005887 ISS:BHF-UCLCintegral component of plasma membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0038106 ISS:BHF-UCLFchoriogonadotropin hormone binding
GO:0035472 ISS:BHF-UCLFchoriogonadotropin hormone receptor activity
GO:0004964 IEA:InterProFluteinizing hormone receptor activity
GO:0007190 ISS:BHF-UCLPactivation of adenylate cyclase activity
GO:0071371 ISS:BHF-UCLPcellular response to gonadotropin stimulus
GO:0050890 IMP:UniProtKBPcognition
GO:0007186 TAS:ProtIncPG-protein coupled receptor signaling pathway
GO:0007187 TAS:ProtIncPG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0030539 TAS:ProtIncPmale genitalia development
GO:0008584 TAS:ProtIncPmale gonad development
GO:0007200 ISS:BHF-UCLPphospholipase C-activating G-protein coupled receptor signaling pathway
GO:0043950 ISS:BHF-UCLPpositive regulation of cAMP-mediated signaling
GO:0032962 ISS:BHF-UCLPpositive regulation of inositol trisphosphate biosynthetic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_19327G alpha (s) signalling events
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_16942Hormone ligand-binding receptors
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
SMP Pathway Links
SMP IDDescription
SMP00338Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin
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