MGP Database

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MGP001818

Ontology/Pathway Information

Entrez Gene ID3981
Gene Nameligase IV, DNA, ATP-dependent
Gene Symbol LIG4
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0000793 IDA:UniProtKBCcondensed chromosome
GO:0005737 IDA:HPACcytoplasm
GO:0005958 ISS:UniProtKBCDNA-dependent protein kinase-DNA ligase 4 complex
GO:0032807 IMP:UniProtKBCDNA ligase IV complex
GO:0005925 IDA:HPACfocal adhesion
GO:0070419 IDA:UniProtKBCnonhomologous end joining complex
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0005886 IDA:HPACplasma membrane
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0003677 IDA:UniProtKBFDNA binding
GO:0003909 IDA:UniProtKBFDNA ligase activity
GO:0003910 IDA:UniProtKBFDNA ligase (ATP) activity
GO:0016874 IDA:UniProtKBFligase activity
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0008022 IPI:UniProtKBFprotein C-terminus binding
GO:0007049 IEA:UniProtKB-KWPcell cycle
GO:0051301 IEA:UniProtKB-KWPcell division
GO:0008283 ISS:UniProtKBPcell proliferation
GO:0007417 ISS:UniProtKBPcentral nervous system development
GO:0051276 ISS:UniProtKBPchromosome organization
GO:0071897 IEA:InterProPDNA biosynthetic process
GO:0006266 IDA:UniProtKBPDNA ligation
GO:0051102 ISS:UniProtKBPDNA ligation involved in DNA recombination
GO:0051103 IDA:UniProtKBPDNA ligation involved in DNA repair
GO:0006281 TAS:ReactomePDNA repair
GO:0006302 IDA:UniProtKBPdouble-strand break repair
GO:0006303 IDA:UniProtKBPdouble-strand break repair via nonhomologous end joining
GO:0075713 TAS:ReactomePestablishment of integrated proviral latency
GO:0001701 ISS:UniProtKBPin utero embryonic development
GO:0045190 ISS:UniProtKBPisotype switching
GO:0006273 IBA:GO_CentralPlagging strand elongation
GO:0043524 ISS:UniProtKBPnegative regulation of neuron apoptotic process
GO:0051402 ISS:UniProtKBPneuron apoptotic process
GO:0006297 IDA:UniProtKBPnucleotide-excision repair, DNA gap filling
GO:0048146 ISS:UniProtKBPpositive regulation of fibroblast proliferation
GO:0050769 ISS:UniProtKBPpositive regulation of neurogenesis
GO:0002328 ISS:UniProtKBPpro-B cell differentiation
GO:0010332 ISS:UniProtKBPresponse to gamma radiation
GO:0010165 IMP:UniProtKBPresponse to X-ray
GO:0000012 IDA:UniProtKBPsingle strand break repair
GO:0035019 ISS:UniProtKBPsomatic stem cell maintenance
GO:0033077 ISS:UniProtKBPT cell differentiation in thymus
GO:0033153 ISS:UniProtKBPT cell receptor V(D)J recombination
GO:0033151 IDA:UniProtKBPV(D)J recombination
GO:0016032 TAS:ReactomePviral process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_90582-LTR circle formation
REACT_116125Disease
REACT_216DNA Repair
REACT_2054Double-Strand Break Repair
REACT_6266Early Phase of HIV Life Cycle
REACT_6185HIV Infection
REACT_6256HIV Life Cycle
REACT_6918Integration of provirus
REACT_1022Nonhomologous End-joining (NHEJ)
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