MGP Database

MGP001823

Ontology/Pathway Information

Entrez Gene ID	3988
Gene Name	lipase A, lysosomal acid, cholesterol esterase
Gene Symbol	LIPA
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0005764	TAS:ProtInc	C	lysosome
GO:0016298	IDA:UniProtKB	F	lipase activity
GO:0004771	IDA:UniProtKB	F	sterol esterase activity
GO:0000902	IEA:Ensembl	P	cell morphogenesis
GO:0008283	IEA:Ensembl	P	cell proliferation
GO:0001816	IEA:Ensembl	P	cytokine production
GO:0048873	IEA:Ensembl	P	homeostasis of number of cells within a tissue
GO:0006954	IEA:Ensembl	P	inflammatory response
GO:0016042	IEA:UniProtKB-KW	P	lipid catabolic process
GO:0030324	IEA:Ensembl	P	lung development
GO:0048771	IEA:Ensembl	P	tissue remodeling

SMP Pathway Links

SMP ID	Description
SMP00720	27-Hydroxylase Deficiency
SMP00095	Alendronate Action Pathway
SMP00131	Atorvastatin Action Pathway
SMP00035	Bile Acid Biosynthesis
SMP00315	Cerebrotendinous Xanthomatosis (CTX)
SMP00111	Cerivastatin Action Pathway
SMP00387	CHILD Syndrome
SMP00508	Cholesteryl ester storage disease
SMP00388	Chondrodysplasia Punctata II, X Linked Dominant (CDPX2)
SMP00314	Congenital Bile Acid Synthesis Defect Type II
SMP00318	Congenital Bile Acid Synthesis Defect Type III
SMP00386	Desmosterolosis
SMP00317	Familial Hypercholanemia (FHCA)
SMP00119	Fluvastatin Action Pathway
SMP00209	Hypercholesterolemia
SMP00509	Hyper-IgD syndrome
SMP00079	Ibandronate Action Pathway
SMP00099	Lovastatin Action Pathway
SMP00319	Lysosomal Acid Lipase Deficiency (Wolman Disease)
SMP00510	Mevalonic aciduria
SMP00117	Pamidronate Action Pathway
SMP00089	Pravastatin Action Pathway
SMP00112	Risedronate Action Pathway
SMP00092	Rosuvastatin Action Pathway
SMP00082	Simvastatin Action Pathway
SMP00389	Smith-Lemli-Opitz Syndrome (SLOS)
SMP00023	Steroid Biosynthesis
SMP00511	Wolman disease
SMP00316	Zellweger Syndrome
SMP00107	Zoledronate Action Pathway