MGP Database

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MGP001826

Ontology/Pathway Information

Entrez Gene ID3992
Gene Namefatty acid desaturase 1
Gene Symbol FADS1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0016021 NAS:UniProtKBCintegral component of membrane
GO:0043231 NAS:UniProtKBCintracellular membrane-bounded organelle
GO:0016020 IDA:UniProtKBCmembrane
GO:0005739 IEA:UniProtKB-SubCellCmitochondrion
GO:0000248 TAS:ProtIncFC-5 sterol desaturase activity
GO:0020037 IEA:InterProFheme binding
GO:0005506 IEA:InterProFiron ion binding
GO:0016491 IDA:UniProtKBFoxidoreductase activity
GO:0036109 TAS:ReactomePalpha-linolenic acid metabolic process
GO:0007267 NAS:UniProtKBPcell-cell signaling
GO:0044255 TAS:ReactomePcellular lipid metabolic process
GO:0009267 IDA:UniProtKBPcellular response to starvation
GO:0046456 TAS:UniProtKBPicosanoid biosynthetic process
GO:0043651 TAS:ReactomePlinoleic acid metabolic process
GO:0008654 TAS:UniProtKBPphospholipid biosynthetic process
GO:0045595 NAS:UniProtKBPregulation of cell differentiation
GO:0006355 NAS:UniProtKBPregulation of transcription, DNA-templated
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006636 IDA:UniProtKBPunsaturated fatty acid biosynthetic process
GO:0033559 TAS:ReactomePunsaturated fatty acid metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_121147alpha-linolenic acid (ALA) metabolism
REACT_121284alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
REACT_22279Fatty acid, triacylglycerol, and ketone body metabolism
REACT_121100Linoleic acid (LA) metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_116145PPARA activates gene expression
REACT_19241Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
SMP Pathway Links
SMP IDDescription
SMP00018Alpha Linolenic Acid and Linoleic Acid Metabolism
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