MGP Database

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MGP001833

Ontology/Pathway Information

Entrez Gene ID4017
Gene Namelysyl oxidase-like 2
Gene Symbol LOXL2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005604 ISS:UniProtKBCbasement membrane
GO:0005694 IEA:UniProtKB-SubCellCchromosome
GO:0005615 IDA:UniProtKBCextracellular space
GO:0016020 IEA:InterProCmembrane
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0003682 IDA:UniProtKBFchromatin binding
GO:0005507 IEA:InterProFcopper ion binding
GO:0009055 TAS:UniProtKBFelectron carrier activity
GO:0035064 IDA:UniProtKBFmethylated histone binding
GO:0070492 IDA:UniProtKBFoligosaccharide binding
GO:0004720 IDA:UniProtKBFprotein-lysine 6-oxidase activity
GO:0005044 IEA:InterProFscavenger receptor activity
GO:0003714 IDA:UniProtKBFtranscription corepressor activity
GO:0007568 TAS:ProtIncPaging
GO:0007155 TAS:ProtIncPcell adhesion
GO:0006464 IDA:UniProtKBPcellular protein modification process
GO:0030199 IMP:UniProtKBPcollagen fibril organization
GO:0043542 IMP:UniProtKBPendothelial cell migration
GO:0001935 IMP:UniProtKBPendothelial cell proliferation
GO:0001837 IDA:UniProtKBPepithelial to mesenchymal transition
GO:0016570 IDA:UniProtKBPhistone modification
GO:0045892 IDA:UniProtKBPnegative regulation of transcription, DNA-templated
GO:0055114 IDA:UniProtKBPoxidation-reduction process
GO:0032332 ISS:UniProtKBPpositive regulation of chondrocyte differentiation
GO:0018277 IDA:UniProtKBPprotein deamination
GO:0046688 IDA:UniProtKBPresponse to copper ion
GO:0001666 ISS:UniProtKBPresponse to hypoxia
GO:0002040 IMP:UniProtKBPsprouting angiogenesis
GO:0006351 IEA:UniProtKB-KWPtranscription, DNA-templated
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_150180Assembly of collagen fibrils and other multimeric structures
REACT_120729Collagen formation
REACT_150206Crosslinking of collagen fibrils
REACT_150366Elastic fibre formation
REACT_118779Extracellular matrix organization
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