MGP Database

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MGP001834

Ontology/Pathway Information

Entrez Gene ID4023
Gene Namelipoprotein lipase
Gene Symbol LPL
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0031225 IEA:UniProtKB-KWCanchored component of membrane
GO:0009986 IEA:EnsemblCcell surface
GO:0042627 IEA:UniProtKB-KWCchylomicron
GO:0031012 IEA:EnsemblCextracellular matrix
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IDA:UniProtKBCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005886 IEA:UniProtKB-SubCellCplasma membrane
GO:0034361 IEA:UniProtKB-KWCvery-low-density lipoprotein particle
GO:0034185 IPI:BHF-UCLFapolipoprotein binding
GO:0008201 IDA:BHF-UCLFheparin binding
GO:0004465 IDA:BHF-UCLFlipoprotein lipase activity
GO:0004620 ISS:BHF-UCLFphospholipase activity
GO:0005102 IPI:BHF-UCLFreceptor binding
GO:0017129 IEA:EnsemblFtriglyceride binding
GO:0004806 IDA:BHF-UCLFtriglyceride lipase activity
GO:0034371 IC:BHF-UCLPchylomicron remodeling
GO:0006633 IDA:BHF-UCLPfatty acid biosynthetic process
GO:0042157 TAS:ReactomePlipoprotein metabolic process
GO:0006644 ISS:BHF-UCLPphospholipid metabolic process
GO:0007603 TAS:ReactomePphototransduction, visible light
GO:0010886 IMP:BHF-UCLPpositive regulation of cholesterol storage
GO:0010744 IC:BHF-UCLPpositive regulation of macrophage derived foam cell differentiation
GO:0010890 IMP:BHF-UCLPpositive regulation of sequestering of triglyceride
GO:0009409 IEA:EnsemblPresponse to cold
GO:0042493 IEA:EnsemblPresponse to drug
GO:0001523 TAS:ReactomePretinoid metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0019432 IEA:EnsemblPtriglyceride biosynthetic process
GO:0019433 IDA:BHF-UCLPtriglyceride catabolic process
GO:0070328 IGI:BHF-UCLPtriglyceride homeostasis
GO:0006641 ISS:BHF-UCLPtriglyceride metabolic process
GO:0034372 IDA:BHF-UCLPvery-low-density lipoprotein particle remodeling
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6841Chylomicron-mediated lipid transport
REACT_111045Developmental Biology
REACT_116125Disease
REACT_160102Diseases associated with visual transduction
REACT_602Lipid digestion, mobilization, and transport
REACT_6823Lipoprotein metabolism
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_24968Retinoid metabolism and transport
REACT_111102Signal Transduction
REACT_27161Transcriptional regulation of white adipocyte differentiation
REACT_160125Visual phototransduction
SMP Pathway Links
SMP IDDescription
SMP00529D-glyceric acidura
SMP00530Familial lipoprotein lipase deficiency
SMP00039Glycerolipid Metabolism
SMP00187Glycerol Kinase Deficiency
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