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MGP001852

Record overview

MGPD IDMGP001852
Gene ID4082
SpeciesHomo sapiens (Human)
Gene Namemyristoylated alanine-rich protein kinase C substrate
Gene Symbol MARCKS
SynonymsMACS; 80K-L; PKCSL; PRKCSL;
Alternate namesmyristoylated alanine-rich C-kinase substrate; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); phosphomyristin; protein kinase C substrate, 80 kDa protein, light chain;
Chromosome6
Map Location6q22.2
SummaryThe protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for MARCKS

Proteins

myristoylated alanine-rich C-kinase substrate
Refseq ID:NP_002347
Protein GI:153070260
UniProt ID:P29966
mRNA ID:NM_002356
Length:332
RefSeq Status:
MGAQFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGA
SPVEKEAPAEGEAAEPGSPTAAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAGGA
AAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQEAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEE
PAAAAASSACAAPSQEAQPECSPEAPPAEAAE
 
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