MGP Database

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MGP001870

Ontology/Pathway Information

Entrez Gene ID4141
Gene Namemethionyl-tRNA synthetase
Gene Symbol MARS
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005829 IBA:GO_CentralCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0016020 IDA:UniProtKBCmembrane
GO:0005739 IEA:EnsemblCmitochondrion
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0004825 TAS:ReactomeFmethionine-tRNA ligase activity
GO:0000049 IEA:UniProtKB-KWFtRNA binding
GO:0010467 TAS:ReactomePgene expression
GO:0006431 IBA:GO_CentralPmethionyl-tRNA aminoacylation
GO:0006418 TAS:ReactomePtRNA aminoacylation for protein translation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_15306Cytosolic tRNA aminoacylation
REACT_71Gene Expression
REACT_15482tRNA Aminoacylation
SMP Pathway Links
SMP IDDescription
SMP00177Cystathionine Beta-Synthase Deficiency
SMP00222Glycine N-methyltransferase Deficiency
SMP00570Homocystinuria-megaloblastic anemia due to defect in cobalamin metabolism, cblG complementation type
SMP00341Hypermethioninemia
SMP00221Methionine Adenosyltransferase Deficiency
SMP00033Methionine Metabolism
SMP00340Methylenetetrahydrofolate Reductase Deficiency (MTHFRD)
SMP00214S-Adenosylhomocysteine (SAH) Hydrolase Deficiency
SMP00029Selenoamino Acid Metabolism
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