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MGP001879

Record overview

MGPD IDMGP001879
Gene ID4158
SpeciesHomo sapiens (Human)
Gene Namemelanocortin 2 receptor (adrenocorticotropic hormone)
Gene Symbol MC2R
SynonymsACTHR;
Alternate namesadrenocorticotropic hormone receptor; ACTH receptor; MC2 receptor; adrenocorticotropin receptor; corticotropin receptor;
Chromosome18
Map Location18p11.2
SummaryMC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene. [provided by RefSeq, May 2014]
OrthologsView orthologs and multiple alignments for MC2R

Proteins

adrenocorticotropic hormone receptor
Refseq ID:NP_000520
Protein GI:4505127
UniProt ID:Q01718
mRNA ID:NM_000529
Length:297
RefSeq Status:
MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVFKNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFET
TADDIIDSLFVLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTGTGITMVIFSHHVPTVITFTSLFPLMLVFILCLYVHMFLLA
RSHTRKISTLPRANMKGAITLTILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSPELRDAFKKMIFCSRYW
 
adrenocorticotropic hormone receptor
Refseq ID:NP_001278840
Protein GI:632794824
UniProt ID:Q01718
mRNA ID:NM_001291911
Length:297
RefSeq Status:
Protein sequence is identical to GI:4505127 (mRNA isoform)
 
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