MGP Database

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MGP001885

Ontology/Pathway Information

Entrez Gene ID4171
Gene Nameminichromosome maintenance complex component 2
Gene Symbol MCM2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0000785 IDA:UniProtKBCchromatin
GO:0005737 IDA:HPACcytoplasm
GO:0042555 IDA:UniProtKBCMCM complex
GO:0015630 IDA:HPACmicrotubule cytoskeleton
GO:0005664 IEA:EnsemblCnuclear origin of replication recognition complex
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 IDA:UniProtKBCnucleus
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0003677 TAS:ProtIncFDNA binding
GO:0003678 IEA:InterProFDNA helicase activity
GO:0003688 IEA:EnsemblFDNA replication origin binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0007049 TAS:ProtIncPcell cycle
GO:0071353 IEA:EnsemblPcellular response to interleukin-4
GO:0006260 TAS:ReactomePDNA replication
GO:0006270 IMP:UniProtKBPDNA replication initiation
GO:0006271 TAS:ReactomePDNA strand elongation involved in DNA replication
GO:0006268 IEA:EnsemblPDNA unwinding involved in DNA replication
GO:0000082 TAS:ReactomePG1/S transition of mitotic cell cycle
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0006334 IEA:EnsemblPnucleosome assembly
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6769Activation of ATR in response to replication stress
REACT_1095Activation of the pre-replicative complex
REACT_2243Assembly of the pre-replicative complex
REACT_115566Cell Cycle
REACT_1538Cell Cycle Checkpoints
REACT_152Cell Cycle, Mitotic
REACT_383DNA Replication
REACT_734DNA Replication Pre-Initiation
REACT_932DNA strand elongation
REACT_1783G1/S Transition
REACT_828G2/M Checkpoints
REACT_1725M/G1 Transition
REACT_21267Mitotic G1-G1/S phases
REACT_1156Orc1 removal from chromatin
REACT_829Regulation of DNA replication
REACT_207Removal of licensing factors from origins
REACT_899S Phase
REACT_2148Switching of origins to a post-replicative state
REACT_2014Synthesis of DNA
REACT_6776Unwinding of DNA
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