MGP Database

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MGP001891

Ontology/Pathway Information

Entrez Gene ID4179
Gene NameCD46 molecule, complement regulatory protein
Gene Symbol CD46
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IDA:UniProtKBCcell surface
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0002079 IEA:UniProtKB-SubCellCinner acrosomal membrane
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0045296 IPI:UniProtKBFcadherin binding
GO:0004872 TAS:ProtIncFreceptor activity
GO:0002250 IC:UniProtKBPadaptive immune response
GO:0006958 IEA:UniProtKB-KWPcomplement activation, classical pathway
GO:0045087 TAS:ReactomePinnate immune response
GO:0032613 IDA:UniProtKBPinterleukin-10 production
GO:0010629 IDA:UniProtKBPnegative regulation of gene expression
GO:0010628 IMP:UniProtKBPpositive regulation of gene expression
GO:0032733 IDA:UniProtKBPpositive regulation of interleukin-10 production
GO:0043382 IDA:UniProtKBPpositive regulation of memory T cell differentiation
GO:0045591 IDA:UniProtKBPpositive regulation of regulatory T cell differentiation
GO:0042102 IDA:UniProtKBPpositive regulation of T cell proliferation
GO:0071636 IDA:UniProtKBPpositive regulation of transforming growth factor beta production
GO:0030449 TAS:ReactomePregulation of complement activation
GO:0008593 IDA:UniProtKBPregulation of Notch signaling pathway
GO:0035581 IDA:UniProtKBPsequestering of extracellular ligand from receptor
GO:0007338 IEA:UniProtKB-KWPsingle fertilization
GO:0002456 IMP:UniProtKBPT cell mediated immunity
GO:0016032 IEA:UniProtKB-KWPviral process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6932Complement cascade
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_118707Regulation of Complement cascade
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