MGP Database

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MGP001909

Ontology/Pathway Information

Entrez Gene ID4233
Gene NameMET proto-oncogene, receptor tyrosine kinase
Gene Symbol MET
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009925 IDA:MGICbasal plasma membrane
GO:0009986 IDA:UniProtKBCcell surface
GO:0005576 IEA:UniProtKB-SubCellCextracellular region
GO:0016021 NAS:UniProtKBCintegral component of membrane
GO:0005887 TAS:ProtIncCintegral component of plasma membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0005008 TAS:ProtIncFhepatocyte growth factor-activated receptor activity
GO:0019903 IPI:UniProtKBFprotein phosphatase binding
GO:0004713 NAS:UniProtKBFprotein tyrosine kinase activity
GO:0000187 IEA:EnsemblPactivation of MAPK activity
GO:0030534 IEA:EnsemblPadult behavior
GO:0007411 TAS:ReactomePaxon guidance
GO:0007420 IEA:EnsemblPbrain development
GO:0048754 IMP:UniProtKBPbranching morphogenesis of an epithelial tube
GO:0008283 TAS:ProtIncPcell proliferation
GO:0007166 NAS:UniProtKBPcell surface receptor signaling pathway
GO:0001886 IDA:UniProtKBPendothelial cell morphogenesis
GO:0042593 IEA:EnsemblPglucose homeostasis
GO:0001889 IEA:EnsemblPliver development
GO:0014812 IEA:EnsemblPmuscle cell migration
GO:0051450 IEA:EnsemblPmyoblast proliferation
GO:0014902 IEA:EnsemblPmyotube differentiation
GO:1901299 IMP:BHF-UCLPnegative regulation of hydrogen peroxide-mediated programmed cell death
GO:0018108 NAS:GOCPpeptidyl-tyrosine phosphorylation
GO:0001890 IEA:EnsemblPplacenta development
GO:0050918 IDA:UniProtKBPpositive chemotaxis
GO:2001028 IMP:UniProtKBPpositive regulation of endothelial cell chemotaxis
GO:0010828 IEA:EnsemblPpositive regulation of glucose transport
GO:0045944 IDA:BHF-UCLPpositive regulation of transcription from RNA polymerase II promoter
GO:0046777 IEA:EnsemblPprotein autophosphorylation
GO:0060665 IEA:EnsemblPregulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
GO:0071526 IDA:UniProtKBPsemaphorin-plexin signaling pathway
GO:0007165 TAS:ProtIncPsignal transduction
GO:0007519 IEA:EnsemblPskeletal muscle tissue development
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18266Axon guidance
REACT_111045Developmental Biology
REACT_19259Sema4D in semaphorin signaling
REACT_19266Sema4D mediated inhibition of cell attachment and migration
REACT_19271Semaphorin interactions
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