MGP Database

MGP001911

Record overview

MGPD IDMGP001911
Gene ID4237
SpeciesHomo sapiens (Human)
Gene Namemicrofibrillar-associated protein 2
Gene Symbol MFAP2
SynonymsMAGP; MAGP1; MAGP-1;
Alternate namesmicrofibrillar-associated protein 2; microfibril-associated glycoprotein 1;
Chromosome1
Map Location1p36.1-p35
SummaryMicrofibrillar-associated protein 2 is a major antigen of elastin-associated microfibrils and a candidate for involvement in the etiology of inherited connective tissue diseases. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
OrthologsView orthologs and multiple alignments for MFAP2

Proteins

microfibrillar-associated protein 2 isoform a precursor
Refseq ID:NP_002394
Protein GI:4505157
UniProt ID:P55001
mRNA ID:NM_002403
Length:183
RefSeq Status:
MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREE
QYPCTRLYSIHRPCKQCLNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC
 
sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1880
peptide sequence: 
MRAAYLFLLFLPAGLLA

mat_peptide: 18..183
product: microfibrillar-associated protein 2 isoform a
calculated_mol_wt: 18963
peptide sequence: 
QGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQC
LNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC sig_peptide: 1..17 calculated_mol_wt: 1937 peptide sequence: MRAAYLFLLFLPGLLAQ mat_peptide: 18..182 product: microfibrillar-associated protein 2 isoform b calculated_mol_wt: 18835 peptide sequence: GQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCL
NEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC sig_peptide: 1..17 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 1880 peptide sequence: MRAAYLFLLFLPAGLLA mat_peptide: 18..183 product: microfibrillar-associated protein 2 isoform a calculated_mol_wt: 18963 peptide sequence: QGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQC
LNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC
 
microfibrillar-associated protein 2 isoform a precursor
Refseq ID:NP_059453
Protein GI:9665259
UniProt ID:P55001
mRNA ID:NM_017459
Length:183
RefSeq Status:
Protein sequence is identical to GI:4505157 (mRNA isoform)
 
sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1880
peptide sequence: 
MRAAYLFLLFLPAGLLA

mat_peptide: 18..183
product: microfibrillar-associated protein 2 isoform a
calculated_mol_wt: 18963
peptide sequence: 
QGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQC
LNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC
 
microfibrillar-associated protein 2 isoform b precursor
Refseq ID:NP_001128719
Protein GI:207028905
UniProt ID:P55001
mRNA ID:NM_001135247
Length:182
RefSeq Status:
MRAAYLFLLFLPGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQ
YPCTRLYSIHRPCKQCLNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC
 
sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1880
peptide sequence: 
MRAAYLFLLFLPAGLLA

mat_peptide: 18..183
product: microfibrillar-associated protein 2 isoform a
calculated_mol_wt: 18963
peptide sequence: 
QGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQC
LNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC sig_peptide: 1..17 calculated_mol_wt: 1937 peptide sequence: MRAAYLFLLFLPGLLAQ mat_peptide: 18..182 product: microfibrillar-associated protein 2 isoform b calculated_mol_wt: 18835 peptide sequence: GQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCL
NEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC sig_peptide: 1..17 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 1880 peptide sequence: MRAAYLFLLFLPAGLLA mat_peptide: 18..183 product: microfibrillar-associated protein 2 isoform a calculated_mol_wt: 18963 peptide sequence: QGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQC
LNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC sig_peptide: 1..17 calculated_mol_wt: 1937 peptide sequence: MRAAYLFLLFLPGLLAQ mat_peptide: 18..182 product: microfibrillar-associated protein 2 isoform b calculated_mol_wt: 18835 peptide sequence: GQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCL
NEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC
 
microfibrillar-associated protein 2 isoform b precursor
Refseq ID:NP_001128720
Protein GI:207028935
UniProt ID:P55001
mRNA ID:NM_001135248
Length:182
RefSeq Status:
Protein sequence is identical to GI:207028905 (mRNA isoform)
 
sig_peptide: 1..17
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1880
peptide sequence: 
MRAAYLFLLFLPAGLLA

mat_peptide: 18..183
product: microfibrillar-associated protein 2 isoform a
calculated_mol_wt: 18963
peptide sequence: 
QGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQC
LNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC sig_peptide: 1..17 calculated_mol_wt: 1937 peptide sequence: MRAAYLFLLFLPGLLAQ mat_peptide: 18..182 product: microfibrillar-associated protein 2 isoform b calculated_mol_wt: 18835 peptide sequence: GQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCL
NEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC
 
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