MGP Database

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MGP001923

Ontology/Pathway Information

Entrez Gene ID4261
Gene Nameclass II, major histocompatibility complex, transactivator
Gene Symbol CIITA
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0016605 IDA:UniProtKBCPML body
GO:0033613 IPI:BHF-UCLFactivating transcription factor binding
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0005525 IEA:UniProtKB-KWFGTP binding
GO:0016301 IEA:UniProtKB-KWFkinase activity
GO:0032403 IDA:UniProtKBFprotein complex binding
GO:0008022 IPI:UniProtKBFprotein C-terminus binding
GO:0003713 TAS:ProtIncFtranscription coactivator activity
GO:0044212 IDA:BHF-UCLFtranscription regulatory region DNA binding
GO:0016746 IEA:UniProtKB-KWFtransferase activity, transferring acyl groups
GO:0019221 TAS:ReactomePcytokine-mediated signaling pathway
GO:0006955 TAS:ProtIncPimmune response
GO:0060333 TAS:ReactomePinterferon-gamma-mediated signaling pathway
GO:0032966 IC:BHF-UCLPnegative regulation of collagen biosynthetic process
GO:0045892 IDA:BHF-UCLPnegative regulation of transcription, DNA-templated
GO:0000122 IMP:BHF-UCLPnegative regulation of transcription from RNA polymerase II promoter
GO:0045345 IDA:BHF-UCLPpositive regulation of MHC class I biosynthetic process
GO:0045348 IC:BHF-UCLPpositive regulation of MHC class II biosynthetic process
GO:0045893 IDA:BHF-UCLPpositive regulation of transcription, DNA-templated
GO:0045944 IDA:BHF-UCLPpositive regulation of transcription from RNA polymerase II promoter
GO:0046677 IDA:MGIPresponse to antibiotic
GO:0034341 IDA:BHF-UCLPresponse to interferon-gamma
GO:0006351 IEA:UniProtKB-KWPtranscription, DNA-templated
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75790Cytokine Signaling in Immune system
REACT_6900Immune System
REACT_25078Interferon gamma signaling
REACT_25229Interferon Signaling
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