MGP Database

MGP001927

Ontology/Pathway Information

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0009897	IEA:Ensembl	C	external side of plasma membrane
GO:0005576	TAS:Reactome	C	extracellular region
GO:0005615	TAS:ProtInc	C	extracellular space
GO:0008009	IDA:UniProtKB	F	chemokine activity
GO:0048248	IDA:UniProtKB	F	CXCR3 chemokine receptor binding
GO:0005125	TAS:ProtInc	F	cytokine activity
GO:0007267	TAS:ProtInc	P	cell-cell signaling
GO:0006968	TAS:ProtInc	P	cellular defense response
GO:0070098	IBA:GO_Central	P	chemokine-mediated signaling pathway
GO:0006935	IDA:UniProtKB	P	chemotaxis
GO:0006952	TAS:ProtInc	P	defense response
GO:0051607	IEA:Ensembl	P	defense response to virus
GO:0007186	TAS:ProtInc	P	G-protein coupled receptor signaling pathway
GO:0006955	IBA:GO_Central	P	immune response
GO:0006954	TAS:ProtInc	P	inflammatory response
GO:0043950	IDA:UniProtKB	P	positive regulation of cAMP-mediated signaling
GO:0030816	IDA:UniProtKB	P	positive regulation of cAMP metabolic process
GO:0002690	IBA:GO_Central	P	positive regulation of leukocyte chemotaxis
GO:0051281	IDA:UniProtKB	P	positive regulation of release of sequestered calcium ion into cytosol
GO:0042127	IDA:UniProtKB	P	regulation of cell proliferation
GO:0032496	IBA:GO_Central	P	response to lipopolysaccharide
GO:0007165	TAS:ProtInc	P	signal transduction
GO:0010818	IBA:GO_Central	P	T cell chemotaxis

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_15344	Chemokine receptors bind chemokines
REACT_14828	Class A/1 (Rhodopsin-like receptors)
REACT_267874	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125	Disease
REACT_19231	G alpha (i) signalling events
REACT_19184	GPCR downstream signaling
REACT_21340	GPCR ligand binding
REACT_267615	Metabolic disorders of biological oxidation enzymes
REACT_14819	Peptide ligand-binding receptors
REACT_14797	Signaling by GPCR
REACT_111102	Signal Transduction